Eurofins-BPT boasts a multitude state of the art, purpose-built biosafety level-2 (BSL-2) molecular and cell biology suites. Our laboratories are fully certified by the European Protection Agency (EPA) to handle GMM/GMOs.
Each of the many BSL-2 laboratories are designed specifically for; cell storage, cell culture, cell based assays, ELISA and PCR (with self-contained PCR reagent preparation and dedicated extraction labs). We work closely with clients to optimise methods for feasibility, transfer, validation and development. All work is performed under strict adherence to cGMP, EP/USP and ICH guidelines.
Our team is comprised of highly skilled molecular and cell biologists with rich industry and academic knowledge, averaging up to 15 years of relevant experience in the field, including method development, optimisation and critical thinking.
Eurofins-BPT, offers clients an unparalleled service, streamlining product release to market.
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Cell-Based Assays/Potency Testing:
- Cytotoxicity Assays / ADCC /CDC
- Signalling assays
- Proliferation assays
- Neutralisation assays
- Reporter gene assays
- Infectivity assays
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ELISA:
- Potency testing
- Ligand binding / Antibody Binding
- Residual protein quantification (eg: Host Cell Protein assays, Benzonase, Protein A, BSA)
- Content/Identity testing
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qPCR:
- Viral content testing
- DNA copy number detection, gene expression, SNP genotyping, adventitious agent detection
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Sequencing:
- Nucleic acid contaminant (DNA/RNA) testing
- Identity testing
- Genetic stability testing
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Instruments:
- Multimode plate readers (absorbance, luminescence, fluorescence, time resolved fluorescence, FRET, FP, HTRF®) Molecular Devices, SpectraMax® M5
- Beckman Coulter Vi-CELL™ cell analyser
- Biosafety cabinets
- CO2 incubators
- BioTek plate washer
- Agilent PCR
- Sanger Sequence
- ddPCR
